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Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr 268 SMILES OC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

SKU 12194433127
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EUR445.00 EUR482.00

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Description

268 SMILES OC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Oregon Green resists fading under prolonged illumination better than fluorescein

emission maximum = 660 nm

S)-AHPC-acetamido-O-C2-Cl Synonyms CAS Number n/a Related CAS Molecular Formula C26H35ClN4O5S Molecular Weight 551

Product Name tert-butyl 2-[4-(piperidin-4-yl)piperazin-1-yl]acetate Synonyms CAS Number 688020-38-4 Related CAS Molecular Formula C15H29N3O2 Molecular Weight 283

Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr 268 SMILES OC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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