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Compared to earlier iterations
Product Name Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C72H96FN9O23 Molecular Weight 1474
Product Name DOTA-tris(t-Bu)ester-PEG5-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C40H76N8O12 Molecular Weight 861
HaXS8 is a synthetic chemical dimerizer designed to induce covalent and irreversible intracellular dimerization between proteins tagged with HaloTag and SNAP-tag
Product Name Fmoc-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C55H72N6O16 Molecular Weight 1073
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-MMAE sir Compared to earlier iterationsSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly
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