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MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95%

SKU 1501120196
4.4
USD495.00 USD519.00

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Description

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-5'-piperazine-C2-OH Synonyms CAS Number 2222115-00-4 Related CAS Molecular Formula C19H22N4O5 Molecular Weight 386

S)-AHPC-CO-C2-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C29H44Cl2N6O4S Molecular Weight 643

Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C60H85N7O16 Molecular Weight 1160

PC-6 is a specially designed fluorescent probe for detecting SARM1 activity

MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers

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