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highlighting its strong affinity and potential as a precision tool in targeted protein degradation studies
Product Name DOTA-tris(t-Bu)ester-PEG2-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C34H64N8O9 Molecular Weight 728
It forms a covalent bond with the CLIP-tag protein
Product Name Lenalidomide-C4-acid Synonyms Lenalidomide-4'-C4-acid CAS Number 2338824-29-4 Related CAS Molecular Formula C18H21N3O5 Molecular Weight 359
CA-N3 is a HaloTag ligand containing an azide functional group
Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan AHPC highlighting its strong affinity andSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent
