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Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Thalidomide-O-PEG2-C2-acid Synonyms Thalidomide-4'-O-PEG2-C2-acid

SKU 25110804726
4.4
EUR445.00 EUR484.00

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Description

Product Name Thalidomide-O-PEG2-C2-acid Synonyms Thalidomide-4'-O-PEG2-C2-acid CAS Number 2488752-64-1 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434

707 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

1038/s41467-023-44237-4

S)-AHPC-CO-C2-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C29H44Cl2N6O4S Molecular Weight 643

SiR-NHS is the NHS ester of SiR-6-COOH (652Ex/674Em) and can be conjugated to amine-containing molecules easily

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Thalidomide-O-PEG2-C2-acid Synonyms Thalidomide-4'-O-PEG2-C2-acidSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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