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Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg Manojkumar

SKU 30198128028
4.2
USD445.00 USD475.00

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Description

Manojkumar

Product Name tert-butyl 4-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}piperazine-1-carboxylate Synonyms CAS Number n/a Related CAS Molecular Formula C17H35N5O2 Molecular Weight 341

Product Name Phthalimidinoglutarimide-C4-amine HCl Synonyms Phthalimidinoglutarimide-4'-C4-amine HCl CAS Number 2093388-69-1 Related CAS Molecular Formula C17H22ClN3O3 Molecular Weight 351

425 SMILES CC(C)(C)OC(=O)N1CCC(CC1)N1CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-tris(t-Bu)ester-pentyne Synonyms CAS Number n/a Related CAS Molecular Formula C33H59N5O7 Molecular Weight 637

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg ManojkumarSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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