DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:50mg 364 SMILES OC(=O)CCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)

364 SMILES OC(=O)CCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

472 Purity (HPLC) >= 95% Solubility DMSO

Product Name Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C85H137N13O25 Molecular Weight 1741

614 Purity (HPLC) >= 95% Physical Appearance White Solid Optical Properties n/a Solubility DMSO

Product Name Thalidomide-5'-O-C3-OH Synonyms CAS Number 2476318-89-3 Related CAS Molecular Formula C16H16N2O6 Molecular Weight 332

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:50mg 364 SMILES OC(=O)CCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further