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Product Name DOTA-pentyne Synonyms CAS Number n/a Related CAS Molecular Formula C21H35N5O7 Molecular Weight 469
92 SMILES Cl
Product Name Thalidomide-O-acetamido-C5-acid Synonyms Thalidomide-4'-O-acetamido-C5-acid CAS Number 2354352-06-8 Related CAS Molecular Formula C21H23N3O8 Molecular Weight 445
5-(and-6)-carboxy-2
S)-AHPC-CO-C2-acid Synonyms CAS Number 2172819-72-4 Related CAS Molecular Formula C26H34N4O6S Molecular Weight 530
MC-Val-Ala-PAB(m-PEG8)-Exatecan ca Product Name DOTA-pentyne Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,
