TMP3-TMR Size:100nmol Targeted protein degraders crowd into

Targeted protein degraders crowd into the clinic

38 SMILES: Cl

43 Purity (HPLC) >= 95% Solubility DMSO

Product Name DOTA-tris(t-Bu)ester-octyne Synonyms CAS Number n/a Related CAS Molecular Formula C36H65N5O7 Molecular Weight 679

Product Name Lenalidomide-CO-C3-OH Synonyms Lenalidomide-4'-CO-C3-OH CAS Number n/a Related CAS Molecular Formula C17H19N3O5 Molecular Weight 345

TMP3-TMR Size:100nmol Targeted protein degraders crowd intoThe TMP tag is based on the tight binding between trimethoprim (TMP), a synthetic antibiotic, and Escherichia coli dihydrofolate reductase (eDHFR), a small enzyme with a high affinity for TMP. By fusing eDHFR to a protein of interest and introducing TMP linked to a probesuch as a fluorescent dye, biotin, or other functional groupresearchers can selectively label and study proteins in their native cellular environment. TMP3 TMR is a third generation