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DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:50mg 959 Purity (HPLC) >= 95%

SKU 41137291264
4.2
USD345.00 USD389.00

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Description

959 Purity (HPLC) >= 95% Solubility DMSO

Product Name Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C87H141N11O26 Molecular Weight 1757

Building Block for DACF1 Binders and PROTACs based on DACF1 Binders

Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C89H151N13O26 Molecular Weight 1819

It promotes degradation of Aiolos and Ikaros proteins

DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:50mg 959 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,

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