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Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan macrophage Product Name CP-CPY Synonyms SNAP2-CPY

SKU 42719982963
4.1
USD445.00 USD493.00

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Ships within 48 hours · Estimated delivery Aug 15 - Aug 20

Description

Product Name CP-CPY Synonyms SNAP2-CPY CAS Number Related CAS Molecular Formula C40H39ClN6O4 Molecular Weight 703

1 Purity (HPLC) >= 95% Physical Appearance Yellow Solid Optical Properties Abs/Em Maxima: 496/516 nm Solubility DMSO

041 Purity (HPLC) >= 95% Solubility DMSO

Product Name CC-92480 Synonyms Mezigdomide CAS Number 2259648-80-9 Related CAS Molecular Formula C32H30FN5O4 Molecular Weight 567

89 SMILES ClCCOCCOCCOCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan macrophage Product Name CP-CPY Synonyms SNAP2-CPYSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU

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