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This two-step mechanism provides high specificity and sensitivity
Degrader building block for targeted protein degradation
rhodamine 6G conjugates have higher fluorescence quantum yields than tetramethylrhodamine conjugates
CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCN2CCNCC2)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
BC-TMR is a CLIP-tag substrate containg 6-tetramethylrhodamine dye and it forms a covalent bond with the CLIP-tag protein
Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Size:50mg This two-step mechanism provides highSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX
