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Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:25mg and strong selectivity for SARM1

SKU 5645342930
4.9
USD445.00 USD495.00

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Description

and strong selectivity for SARM1 over other NADases

Contains Cy3 fluorophore

Product Name CP- diAcFAM Synonyms SNAP2- diAcFAM CAS Number Related CAS Molecular Formula C37H27ClN4O9 Molecular Weight 707

Product Name Pomalidomide-C4-Br Synonyms Pomalidomide-4'-C4-Br CAS Number 2355289-79-9 Related CAS Molecular Formula C17H18BrN3O4 Molecular Weight 408

69 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:25mg and strong selectivity for SARM1SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous

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