DBCO-Dap(m-PEG4)-Val-Ala-PAB dbco-dap-m-PEG4 Product Name Thalidomide-O-acetamido-PEG6-OH Synonyms Thalidomide-4'-O-acetamido-PEG6-OH

Product Name Thalidomide-O-acetamido-PEG6-OH Synonyms Thalidomide-4'-O-acetamido-PEG6-OH CAS Number n/a Related CAS Molecular Formula C25H33N3O11 Molecular Weight 551

Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C63H91N9O17 Molecular Weight 1246

Product Name Lenalidomide-CO-C3-acid Synonyms Lenalidomide-4'-CO-C3-acid CAS Number 1334496-37-5 Related CAS Molecular Formula C18H19N3O6 Molecular Weight 373

403 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCCOCCOCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Building Block for DACF1 Binders and PROTACs based on DACF1 Binders

DBCO-Dap(m-PEG4)-Val-Ala-PAB dbco-dap-m-PEG4 Product Name Thalidomide-O-acetamido-PEG6-OH Synonyms Thalidomide-4'-O-acetamido-PEG6-OHSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,