Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan chemical 84 SMILES Cl

84 SMILES Cl

Product Name Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C59H95N11O23 Molecular Weight 1326

Product Name GW5074 Synonyms 10O5

TAMRA TMR) is a bright orange fluorophore and one of the most popular fluorophores used in various bioconjugations

438 SMILES OCCCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan chemical 84 SMILES ClSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,