DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-PNP Size:50mg 85 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCC(O)=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)

85 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCC(O)=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

407 SMILES OCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

piperidinyl)

Product Name CA-Lissamine Rhodamine B Synonyms Lissamine Rhodamine B Halotag Ligand CAS Number N/A Related CAS N/A Molecular Formula C37H50ClN3O8S2 Molecular Weight 764

717 SMILES NCCOCCOCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-PNP Size:50mg 85 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCC(O)=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine