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A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase
Signal Transduction and Targeted Therapy
Product Name Pomalidomide-PEG6-C2-acid Synonyms Pomalidomide-4'-PEG6-C2-acid CAS Number 2225148-49-0 Related CAS Molecular Formula C28H39N3O12 Molecular Weight 609
Product Name Thalidomide-propargyl-O-PEG5-OH Synonyms Thalidomide-4'-propargyl-O-PEG5-OH CAS Number n/a Related CAS Molecular Formula C26H32N2O10 Molecular Weight 532
79 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)OCC#C)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only
BG-Cp Size:100nmol A novel cereblon modulator recruitsSNAP tag is a self labeling protein derived from human O6 alkylguanine DNA alkyltransferase. At 20 kDa, SNAP tag is smaller than HaloTag (33 kDa), potentially reducing interference with the tagged proteins function. SNAP tag reacts with covalently with benzylguanine (BG)or chloropyrimidine (CP) derivatives, forming a stable thioether bonds that ensures durability for long term experiments or harsh conditions. SNAP tag can be used alongside other tags
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