DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-aldehyde S)-AHPC-acetamido-O-PEG4-C1-acid Synonyms CAS Number 2172820-13-0

S)-AHPC-acetamido-O-PEG4-C1-acid Synonyms CAS Number 2172820-13-0 Related CAS Molecular Formula C34H50N4O11S Molecular Weight 722

664 SMILES NCCOCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

297 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

821 Purity (HPLC) >= 95% Solubility DMSO

97 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCCN=[N]#N)C3=CC=C(C=C3C2(C)C)S(O)(=O)=O)N(CCCS([O-])(=O)=O)C2=CC=C(C=C12)S(O)(=O)=O Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-aldehyde S)-AHPC-acetamido-O-PEG4-C1-acid Synonyms CAS Number 2172820-13-0SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate