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Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg It is used to modify

SKU 73290368428
4.7
USD445.00 USD470.00

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Description

It is used to modify amino and hydroxy groups using EDC-mediated couplings when there are difficulties in using 5(6)-TAMRA

Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C41H53N7O16 Molecular Weight 899

064 SMILES [H]C(=O)C1=CC=C(Br)C(OC([2H])([2H])[2H])=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

MaP555 is a small-molecule fluorogenic probe with excellent cell permeability

Py-BODIPY (576Ex/589Em) is widely used for its sharp absorption and emission peaks

Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg It is used to modifySOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU

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