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S)-AHPC-CO-C5-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C32H50Cl2N6O4S Molecular Weight 685
specifically used in the strain-promoted azide-alkyne cycloaddition (SPAAC) reaction
Product Name Phthalimidinoglutarimide-C5-Br Synonyms Phthalimidinoglutarimide-4'-C5-Br CAS Number n/a Related CAS Molecular Formula C18H21BrN2O3 Molecular Weight 393
linking two molecules covalently
NCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan acid-acid S)-AHPC-CO-C5-piperazine HCl Synonyms CAS NumberSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
