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Fmoc-Val-Cit-PAB-PNP Size:100mg Product Name DOTA-PEG3-C2-amine Synonyms CAS

SKU 75449697317
4.1
USD90.00 USD124.00

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Description

Product Name DOTA-PEG3-C2-amine Synonyms CAS Number 2866181-79-3 Related CAS Molecular Formula C24H46N6O10 Molecular Weight 578

Product Name Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C61H95N9O24 Molecular Weight 1338

Product Name DOTA-tris(t-Bu)ester-C6-azide Synonyms CAS Number n/a Related CAS Molecular Formula C34H64N8O7 Molecular Weight 696

Product Name 1-[2-(piperazin-1-yl)ethyl]piperazine Synonyms CAS Number 19479-83-5 Related CAS Molecular Formula C10H22N4 Molecular Weight 198

513 SMILES OCCOCCOCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Cit-PAB-PNP Size:100mg Product Name DOTA-PEG3-C2-amine Synonyms CASFmoc Val Cit PAB PNP is a cleavable ADC linker used in antibodydrug conjugate (ADC) development, designed to enable enzyme responsive payload release in tumor targeted applications. The ValCit dipeptide is optimized for cathepsin B cleavage in lysosomal environments, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug. The p nitrophenyl (PNP) group functions as an efficient leaving group for conjugation to

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