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Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C85H105FN10O21 Molecular Weight 1621
75 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
11 Purity (HPLC) >= 95% Solubility DMSO
Product Name 1-[2-(piperazin-1-yl)ethyl]piperazine Synonyms CAS Number 19479-83-5 Related CAS Molecular Formula C10H22N4 Molecular Weight 198
Product Name Pomalidomide-C4-azide Synonyms Pomalidomide-4'-C4-azide CAS Number 2758431-96-6 Related CAS Molecular Formula C17H18N6O4 Molecular Weight 370
Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:1mg Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent
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