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Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-MMAE ala Product Name Fmoc-Val-Cit-PAB(m-PEG4) Synonyms CAS

Description

Product Name Fmoc-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C43H58N6O11 Molecular Weight 834

Product Name Phthalimidinoglutarimide-5'-C4-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C17H22ClN3O3 Molecular Weight 351

Product Name Pomalidomide-PEG2-C2-Br Synonyms Pomalidomide-4'-PEG2-C2-Br CAS Number n/a Related CAS Molecular Formula C19H22BrN3O6 Molecular Weight 468

075 Purity (HPLC) >= 95% Solubility DMSO

This two-step mechanism provides high specificity and sensitivity

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-MMAE ala Product Name Fmoc-Val-Cit-PAB(m-PEG4) Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

Exchange/Return Notes