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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Size:100mg resulting in decreased CDK12 substrate

SKU 79263367311
4.3
USD445.00 USD474.00

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Description

resulting in decreased CDK12 substrate phosphorylation

Westermann

Product Name Ac-Lys(Suc)-AMC Synonyms CAS Number N/A Related CAS N/A Molecular Formula C22H27N3O7 Molecular Weight 445

Product Name Pomalidomide-5'-PEG6-OH Synonyms CAS Number 2641838-86-8 Related CAS Molecular Formula C25H35N3O10 Molecular Weight 537

392 Purity (HPLC) >= 95% Solubility DMSO

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Size:100mg resulting in decreased CDK12 substrateSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload

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