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MC-Val-Cit-PAB(m-PEG8)-Exatecan tamra Product Name Lenalidomide-CO-C4-alkyne Synonyms Lenalidomide-4'-CO-C4-alkyne

SKU 80518422936
4.2
USD495.00 USD523.00

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Description

Product Name Lenalidomide-CO-C4-alkyne Synonyms Lenalidomide-4'-CO-C4-alkyne CAS Number n/a Related CAS Molecular Formula C20H21N3O4 Molecular Weight 367

Product Name Pomalidomide-5'-C6-OH Synonyms CAS Number 2493430-98-9 Related CAS Molecular Formula C19H23N3O5 Molecular Weight 373

097 SMILES [2H]C([2H])([2H])NCC1=CC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-C3-azide Synonyms Thalidomide-4'-O-acetamido-C3-azide CAS Number n/a Related CAS Molecular Formula C18H18N6O6 Molecular Weight 414

Product Name DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C72H98N8O24 Molecular Weight 1459

MC-Val-Cit-PAB(m-PEG8)-Exatecan tamra Product Name Lenalidomide-CO-C4-alkyne Synonyms Lenalidomide-4'-CO-C4-alkyneSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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