Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg 972 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)

972 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Development of BODIPY FL VH032 as a High-Affinity and Selective von Hippel-Lindau E3 Ligase Fluorescent Probe and Its Application in a Time-Resolved Fluorescence Resonance Energy-Transfer Assay

Product Name DOTA-tris(t-Bu)ester-C2-acid Synonyms CAS Number n/a Related CAS Molecular Formula C31H57N5O9 Molecular Weight 643

179 Purity (HPLC) >= 95% Solubility DMSO

When introduced to cells

Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg 972 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing