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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan fmoc propargylamide CAS Number: N/A Molecular

SKU 8066056511
4.4
USD495.00 USD517.00

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Description

propargylamide CAS Number: N/A Molecular Formula: C28H25N3O4 Molecular Weight: 467

823 Purity (HPLC) >= 95% Solubility DMSO

Product Name: Thalidomide-O-C3-amine Synonyms: CAS Number: n/a Molecular Formula: C16H18ClN3O5 Molecular Weight: 367

379 SMILES OCCCCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Biotin alkyne is used for the preparation of various biotinylated conjugates via Click Chemistry

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan fmoc propargylamide CAS Number: N/A MolecularSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage

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