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Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg Tasisulam inhibits mitotic progression and

SKU 81606925103
4.4
USD495.00 USD533.00

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Description

Tasisulam inhibits mitotic progression and induces vascular normalization

4 Purity (HPLC) >= 95% Solubility DMSO

BG- diAcFAM is a SNAP-tag substrate containg diAcFAM dye

https://clinicaltrials

The water soluble 5(6)-FAM PEG3 alkyne has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal acetylene group

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg Tasisulam inhibits mitotic progression andSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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