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Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 916 Purity (HPLC) >= 95%

SKU 8263169872
4.7
USD445.00 USD472.00

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Description

916 Purity (HPLC) >= 95% Solubility DMSO

Product Name Mal-Lys(m-PEG4)-Val-Cit-PAB Synonyms CAS Number Related CAS Molecular Formula C38H59N7O12 Molecular Weight 805

Product Name tert-butyl 4-(piperazin-1-yl)butanoate Synonyms CAS Number n/a Related CAS Molecular Formula C12H24N2O2 Molecular Weight 228

Product Name Lenalidomide Synonyms Lenalidomide CAS Number 191732-72-6 Related CAS Molecular Formula C13H13N3O3 Molecular Weight 259

85 SMILES Cl

Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 916 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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