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The payload is monomethyl auristatin E (MMAE)
308 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Phthalimidinoglutarimide-propargyl-C1-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-C1-OH CAS Number 2207541-23-7 Related CAS Molecular Formula C17H16N2O4 Molecular Weight 312
Product Name Pomalidomide-CO-C6-Br Synonyms Pomalidomide-4'-CO-C6-Br CAS Number n/a Related CAS Molecular Formula C20H22BrN3O5 Molecular Weight 464
HaXS8 bridges HaloTag and SNAP-tag fusion proteins by reacting covalently with their respective active sites: the chloroalkane binds irreversibly to HaloTag’s modified dehalogenase pocket
Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE gly The payload is monomethyl auristatinSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
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