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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP protac precursor 349 Purity (HPLC) >= 95%

SKU 88742756336
4.5
USD445.00 USD494.00

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Description

349 Purity (HPLC) >= 95% Solubility DMSO

409 SMILES OCCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-hexyne Synonyms CAS Number n/a Related CAS Molecular Formula C22H37N5O7 Molecular Weight 483

Product Name 1-[2-(piperazin-1-yl)ethyl]piperazine Synonyms CAS Number 19479-83-5 Related CAS Molecular Formula C10H22N4 Molecular Weight 198

407 SMILES OCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP protac precursor 349 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation

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