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Product Name Phthalimidinoglutarimide-propargyl-PEG1-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG1-OH CAS Number n/a Related CAS Molecular Formula C18H18N2O5 Molecular Weight 342
DOTA bifucational chelator containing an alcohol group
Azidobenzoyl-CA CAS Number Related CAS Molecular Formula C17H25ClN4O3 Molecular Weight 368
009 Purity (HPLC) >= 95% Solubility DMSO
Ready for conjugation to a target protein ligand to form PROTACs containing 5'-substituted Thalidomide as cereblon ligand
Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg Product Name Phthalimidinoglutarimide-propargyl-PEG1-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG1-OHSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a
