Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan ggfg Development of BODIPY FL Thalidomide

Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay

such as  MRI contrast agents

propargylamide CAS Number: N/A Molecular Formula: C24H15NO6 Molecular Weight: 413

6-ROX azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through the well known click chemitry

MaP555-Azide is a highly cell-permeable andis a fluorogenic probe

Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan ggfg Development of BODIPY FL ThalidomideSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload